Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23625930 | 1.00 | L3MBTL1 (0.40) | L3MBTL1CA2CYP3A4AHRBCL2L1 | |
| SCHEMBL1751672 | 0.86 | AHR (0.53) | CYP3A4AHRABCG2MEN1KMT2A | |
| SCHEMBL30952913 | 0.84 | MAPT (0.45) | L3MBTL1AHRMEN1KMT2ANPC1 | |
| SCHEMBL23625921 | 0.84 | MAPT (0.45) | L3MBTL1AHRMEN1KMT2ANPC1 | |
| SCHEMBL24824320 | 0.80 | SMN1; SMN2 (0.50) | L3MBTL1AHRMEN1KMT2ANPC1 | |
| SCHEMBL30040831 | 0.78 | MAPT (0.55) | L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3133466 | 0.77 | CYP2A6 (0.48) | CYP3A4AHRBCL2L1MCL1BAK1 | |
| SCHEMBL8930679 | 0.73 | ABCG2 (0.53) | L3MBTL1CYP3A4MCL1ABCG2MEN1 | |
| SCHEMBL28477527 | 0.72 | AHR (0.44) | L3MBTL1CA2CYP3A4AHRPOLB | |
| SCHEMBL1650073 | 0.72 | L3MBTL1 (0.39) | L3MBTL1CA2CYP3A4BCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767090-B | Tricyclic compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-05-28 | — | — | CN | disclosed |