Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23625921 | 1.00 | MAPT (0.45) | MAPTLMNAHTTBLMSMN1; SMN2 | |
| SCHEMBL30040831 | 0.93 | MAPT (0.55) | MAPTLMNAHTTBLMSMN1; SMN2 | |
| SCHEMBL24824320 | 0.90 | SMN1; SMN2 (0.50) | MAPTLMNAHTTBLMSMN1; SMN2 | |
| SCHEMBL3526305 | 0.86 | AHR (0.53) | MAPTLMNAHTTBLMSMN1; SMN2 | |
| SCHEMBL30952891 | 0.84 | L3MBTL1 (0.40) | SMN1; SMN2AHRKMT2AMEN1L3MBTL1 | |
| SCHEMBL23625930 | 0.84 | L3MBTL1 (0.40) | SMN1; SMN2AHRKMT2AMEN1L3MBTL1 | |
| SCHEMBL30041891 | 0.80 | MAPT (0.47) | MAPTLMNAHTTBLMSMN1; SMN2 | |
| SCHEMBL14583969 | 0.79 | MAPT (0.61) | MAPTLMNAHTTBLMSMN1; SMN2 | |
| SCHEMBL31633230 | 0.79 | MAPT (0.61) | MAPTLMNAHTTBLMSMN1; SMN2 | |
| SCHEMBL24824322 | 0.77 | SMN1; SMN2 (0.43) | MAPTLMNAHTTBLMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767090-B | Tricyclic compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-05-28 | — | — | CN | disclosed |