Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | XRCC6 | P12956 | 1/20 | 0.37 |
| ▸ | XRCC5 | P13010 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220365 | 1.00 | PRKDC (0.40) | PRKDCFAAHELANEPIK3CBGPR119 | |
| SCHEMBL23625914 | 0.84 | PRKDC (0.43) | PRKDCFAAHELANEPIK3CBPIK3CG | |
| SCHEMBL23625917 | 0.81 | GPR119 (0.43) | PRKDCFAAHELANEPIK3CBGPR119 | |
| SCHEMBL30952884 | 0.79 | FAAH (0.42) | PRKDCFAAHELANEPIK3CBGPR119 | |
| SCHEMBL24961378 | 0.79 | GPR119 (0.43) | PRKDCFAAHELANEPIK3CBGPR119 | |
| SCHEMBL30952895 | 0.79 | GPR119 (0.43) | PRKDCFAAHELANEPIK3CBGPR119 | |
| SCHEMBL14824496 | 0.77 | FAAH (0.44) | PRKDCFAAHELANEGPR119IRAK4 | |
| SCHEMBL14810195 | 0.73 | FAAH (0.42) | PRKDCFAAHELANEPIK3CBGPR119 | |
| SCHEMBL14809824 | 0.73 | IRAK4 (0.49) | PRKDCFAAHELANEGPR119IRAK4 | |
| SCHEMBL24961380 | 0.72 | PKM (0.44) | PRKDCFAAHELANEIRAK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767090-B | Tricyclic compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-05-28 | — | — | CN | disclosed |