Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24961545 | 1.00 | LMNA (0.56) | LMNATDP1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL23625904 | 0.84 | LMNA (0.39) | LMNATDP1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL24823387 | 0.83 | NPC1 (0.46) | LMNATDP1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL30311035 | 0.83 | NPC1 (0.46) | LMNATDP1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL24824154 | 0.83 | NPC1 (0.46) | LMNATDP1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL30310925 | 0.83 | NPC1 (0.46) | LMNATDP1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL24823308 | 0.82 | ALDH1A1 (0.40) | LMNATDP1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL6014247 | 0.82 | LMNA (0.53) | LMNATDP1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL23625902 | 0.80 | LMNA (0.48) | LMNATDP1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL24826088 | 0.80 | KDM4E (0.41) | LMNASMN1; SMN2HSD17B10MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767090-B | Tricyclic compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-05-28 | — | — | CN | disclosed |