SCHEMBL30952937

SCHEMBL30952937

O=C(CCC(F)(F)F)NC(c1ccncc1)C1CC1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TRPV1 Q8NER1 3/20 0.44
▸ PRCP P42785 2/20 0.40
▸ PDE2A O00408 4/20 0.39
▸ CDK2 P24941 1/20 0.37
▸ AKT1 P31749 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953420 0.83 SMYD3 (0.38) PDE2A
SCHEMBL30953245 0.76 NR3C2 (0.36) TRPV1PDE2A
SCHEMBL30953539 0.75 IGF1R (0.36) —
SCHEMBL23985982 0.75 NPC1 (0.34) —
SCHEMBL30173667 0.75 NPC1 (0.34) —
SCHEMBL30953361 0.74 RAB9A (0.35) TRPV1PDE2A
SCHEMBL30253563 0.74 GPR139 (0.35) TRPV1
SCHEMBL30209654 0.73 NPC1 (0.34) PDE2A
SCHEMBL23985789 0.73 NPC1 (0.34) PDE2A
SCHEMBL30953425 0.72 NR3C2 (0.34) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP claimed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO claimed
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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