SCHEMBL30953308

SCHEMBL30953308

Cn1nccc1C(=O)N[C@@H](COC(C)(C)C(F)(F)F)C(=O)Nc1cc(CN2C[C@@H](C(F)(F)F)NC2=O)ccn1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ IL17A Q16552 4/20 0.33
▸ SLC5A1 P13866 2/20 0.31
▸ CDK2 P24941 2/20 0.30
▸ CCNE1 P24864 1/20 0.30
▸ GSK3B P49841 1/20 0.30
▸ HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953083 0.94 IL17A (0.34) IL17ACDK2CCNE1GSK3B
SCHEMBL30953412 0.86 IGF1R (0.38) SLC5A1
SCHEMBL30953414 0.86 IGF1R (0.38) SLC5A1
SCHEMBL30953106 0.86 IL17A (0.39) IL17ASLC5A1
SCHEMBL30953040 0.85 IL17A (0.47) IL17A
SCHEMBL30953017 0.84 IL17A (0.36) IL17ACDK2CCNE1GSK3B
SCHEMBL30952933 0.84 IL17A (0.37) IL17AHTT
SCHEMBL30952940 0.83 IL17A (0.39) IL17ACDK2CCNE1GSK3B
Hydrochloric Acid SCHEMBL30953395 0.82 SLC5A1 (0.33) IL17ASLC5A1
SCHEMBL30952976 0.82 IL17A (0.36) IL17ACDK2CCNE1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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