Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.44 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18628862 | 0.75 | CNR2 (0.40) | L3MBTL1MAP3K7TAB1GSK3AGSK3B | |
| SCHEMBL18113739 | 0.75 | MAPT (0.46) | L3MBTL1ALDH1A1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL18628963 | 0.74 | MAP3K7 (0.42) | L3MBTL1MAP3K7TAB1ALDH1A1GSK3A | |
| SCHEMBL18628847 | 0.73 | MAP3K7 (0.41) | L3MBTL1MAP3K7TAB1ALDH1A1GSK3A | |
| SCHEMBL10569355 | 0.72 | ALDH1A1 (0.45) | L3MBTL1MAP3K7TAB1ALDH1A1MAPT | |
| SCHEMBL2716927 | 0.71 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1POLBMAPK1RXRA | |
| SCHEMBL2716074 | 0.71 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1POLBMAPK1RXRA | |
| SCHEMBL17542119 | 0.70 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1POLBMAPK1MAPT | |
| SCHEMBL11786417 | 0.70 | CA12 (0.50) | L3MBTL1ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL14762361 | 0.70 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1POLBMAPK1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140431-A1 | COMPOUNDS COMPRISING HETEROARYL RINGS AND COMPOSITIONS AND METHODS THEREOF | IONGEN THERAPEUTICS CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |