Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244784 | 0.87 | MAPT (0.39) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL29178655 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL16702537 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL9741879 | 0.75 | MAP3K7 (0.40) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL30953676 | 0.72 | L3MBTL1 (0.50) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL21940465 | 0.71 | ALDH1A1 (0.47) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL24208543 | 0.71 | ALDH1A1 (0.47) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL9741538 | 0.71 | MAP3K7 (0.37) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL29178708 | 0.71 | ADORA2A (0.37) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL9875106 | 0.70 | KDM4E (0.40) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4840662-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1989-06-20 | — | — | US | disclosed |
| EP-0132826-B1 | N-(1-NITROPHENYL)-5-AMINOPYRIMIDINE DERIVATIVES, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1988-09-28 | — | — | EP | disclosed |
| EP-0132826-A1 | N-(1-nitrophenyl)-5-aminopyrimidine derivatives, their preparation and use | CIBA-GEIGY AG (CH) | 1985-02-13 | — | — | EP | disclosed |