Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599315 | 0.86 | POLB (0.46) | FLT4KDRPOLBTDP1MAPK1 | |
| SCHEMBL30953680 | 0.84 | ALDH1A1 (0.42) | FLT4KDRPOLBTDP1CA12 | |
| SCHEMBL18113739 | 0.74 | MAPT (0.46) | TSHRMAPK1HSD17B10KDM4EKMT2A | |
| SCHEMBL1505151 | 0.74 | GRM4 (0.40) | HCAR3TDP1TSHRMAPK1PADI4 | |
| SCHEMBL18113766 | 0.74 | ALDH1A1 (0.42) | FLT4KDRPOLBTDP1MAPK1 | |
| SCHEMBL30843159 | 0.73 | POLB (0.37) | FLT4KDRPOLBTDP1MAPK1 | |
| SCHEMBL30953805 | 0.73 | NNMT (0.39) | FLT4KDRPOLBTDP1MAPK1 | |
| Hydrochloric Acid SCHEMBL10558900 | 0.72 | ALDH1A1 (0.41) | FLT4KDRPOLBTDP1MAPK1 | |
| SCHEMBL3448711 | 0.72 | CNR1 (0.40) | HCAR3TDP1TSHRMAPK1PADI4 | |
| SCHEMBL18113749 | 0.71 | L3MBTL1 (0.40) | FLT4KDRPOLBTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140431-A1 | COMPOUNDS COMPRISING HETEROARYL RINGS AND COMPOSITIONS AND METHODS THEREOF | IONGEN THERAPEUTICS CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |