Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.66 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27455408 | 1.00 | CRHBP (0.66) | CRHBPCRHR2SMN1; SMN2MAPTGFER | |
| SCHEMBL22148686 | 0.84 | GRIN2D (0.50) | CRHBPCRHR2SMN1; SMN2MAPTGFER | |
| SCHEMBL5788921 | 0.81 | CRHBP (0.96) | CRHBPCRHR2SMN1; SMN2MAPTGFER | |
| SCHEMBL24313224 | 0.80 | CRHBP (1.00) | CRHBPCRHR2SMN1; SMN2MAPTGFER | |
| SCHEMBL6600071 | 0.80 | CRHBP (1.00) | CRHBPCRHR2SMN1; SMN2MAPTGFER | |
| SCHEMBL1616232 | 0.78 | HRH4 (0.72) | CRHBPCRHR2SMN1; SMN2MAPTGFER | |
| SCHEMBL29481713 | 0.77 | NOS3 (0.53) | CRHBPCRHR2SMN1; SMN2HRH3HRH4 | |
| SCHEMBL22122597 | 0.77 | NOS3 (0.53) | CRHBPCRHR2SMN1; SMN2HRH3HRH4 | |
| SCHEMBL29481712 | 0.77 | NOS3 (0.53) | CRHBPCRHR2SMN1; SMN2HRH3HRH4 | |
| SCHEMBL27457591 | 0.77 | GBA1 (0.47) | CRHBPCRHR2SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137984-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |