Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.30 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954736 | 1.00 | OPRD1 (0.35) | OPRD1NR1H2PDK2CA12CA1 | |
| SCHEMBL30954703 | 0.83 | BACE1 (0.34) | PDK2 | |
| SCHEMBL30954745 | 0.76 | OPRD1 (0.42) | OPRD1CA12CA1CA2CA9 | |
| SCHEMBL25867611 | 0.71 | OPRD1 (0.39) | OPRD1CA12CA1CA2CA9 | |
| SCHEMBL17797497 | 0.69 | NR1H2 (0.38) | NR1H2PDK2DRD2GLAPOLB | |
| Hydrochloric Acid SCHEMBL30954709 | 0.69 | OPRD1 (0.44) | OPRD1CA12CA1CA2CA9 | |
| SCHEMBL30954742 | 0.68 | OPRD1 (0.43) | OPRD1CA12CA1CA2CA9 | |
| SCHEMBL2060286 | 0.67 | DRD2 (0.52) | NR1H2DRD2 | |
| SCHEMBL12006122 | 0.67 | NR1H2 (0.35) | NR1H2PDK2DRD2 | |
| SCHEMBL18491763 | 0.65 | DRD2 (0.47) | NR1H2DRD2CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125488-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 浙江海正药业股份有限公司 | 2024-06-20 | — | — | WO | disclosed |