Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25866229 | 0.80 | BRD4 (0.34) | OPRD1MAPTKMT2A | |
| SCHEMBL25867611 | 0.77 | OPRD1 (0.39) | OPRD1MAPTKDM4EGAACA12 | |
| SCHEMBL21788649 | 0.77 | OPRD1 (0.45) | OPRD1 | |
| SCHEMBL30954734 | 0.76 | OPRD1 (0.35) | OPRD1GAACA12CA1CA2 | |
| SCHEMBL30954736 | 0.76 | OPRD1 (0.35) | OPRD1GAACA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL30954709 | 0.76 | OPRD1 (0.44) | OPRD1MAPTKDM4EGAACA12 | |
| SCHEMBL30954742 | 0.75 | OPRD1 (0.43) | OPRD1MAPTKDM4EGAACA12 | |
| SCHEMBL16675996 | 0.73 | AVPR1A (0.38) | OPRD1KDM4EGAAALDH1A1 | |
| SCHEMBL30648685 | 0.73 | CA9 (0.38) | OPRD1MAPTKDM4EGAACA12 | |
| SCHEMBL26640593 | 0.73 | CA9 (0.38) | OPRD1MAPTKDM4EGAACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125488-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 浙江海正药业股份有限公司 | 2024-06-20 | — | — | WO | disclosed |