Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12164932 | 0.89 | SLC6A4 (0.39) | BRD4SLC6A4 | |
| SCHEMBL25867739 | 0.88 | CHRNA7 (0.35) | OPRD1 | |
| SCHEMBL17586458 | 0.85 | OPRD1 (0.39) | OPRD1 | |
| SCHEMBL30476262 | 0.84 | BRD4 (0.33) | BRD4PKMKDM1ABACE1TP53 | |
| SCHEMBL31515349 | 0.80 | KDM1A (0.40) | KDM1AMAPTOPRD1 | |
| SCHEMBL30954745 | 0.80 | OPRD1 (0.42) | MAPTKMT2AOPRD1 | |
| SCHEMBL30954699 | 0.77 | KDM1A (0.38) | KDM1ABACE1OPRD1 | |
| SCHEMBL21788649 | 0.77 | OPRD1 (0.45) | OPRD1 | |
| SCHEMBL25866296 | 0.77 | BACE1 (0.37) | SLC6A4KDM1ABACE1MAPT | |
| SCHEMBL30954703 | 0.76 | BACE1 (0.34) | SLC6A4BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125488-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 浙江海正药业股份有限公司 | 2024-06-20 | — | — | WO | disclosed |
| WO-2023134656-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | 上海壹典医药科技开发有限公司 | 2023-07-20 | — | — | WO | disclosed |