Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17146029 | 1.00 | NOTUM (0.54) | NOTUMNPC1MAPTMGLLALDH1A1 | |
| SCHEMBL14961833 | 0.80 | ACLY (0.39) | NOTUMNPC1MAPTMGLLALDH1A1 | |
| SCHEMBL24921498 | 0.77 | HTT (0.57) | NPC1MAPTMGLLALDH1A1ADRB1 | |
| SCHEMBL24921164 | 0.77 | ADORA2A (0.49) | NOTUMNPC1MAPTMGLLALDH1A1 | |
| SCHEMBL29635591 | 0.76 | NOTUM (0.63) | NOTUMNPC1MAPTMGLLALDH1A1 | |
| SCHEMBL254803 | 0.76 | NOTUM (0.63) | NOTUMNPC1MAPTMGLLALDH1A1 | |
| SCHEMBL24921192 | 0.74 | CHRNB2 (0.49) | DYRK1ACLK4CYP1A2CYP3A4 | |
| SCHEMBL15577161 | 0.74 | ADORA2A (0.56) | NOTUMNPC1MAPTMGLLALDH1A1 | |
| SCHEMBL14320537 | 0.73 | ALDH1A1 (0.42) | NPC1MAPTALDH1A1PKMDYRK1A | |
| SCHEMBL8217706 | 0.73 | NOTUM (0.47) | NOTUMNPC1MAPTMGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125395-A1 | SUBSTITUTED TETRAHYDROCYCLOPENTYL[C]PYRROLE DERIVATIVE, PREPARATION METHOD, INTERMEDIATE AND USE THEREOF | 江苏恩华药业股份有限公司 | 2024-06-20 | — | — | WO | disclosed |