Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3098009 | 0.85 | TSHR (0.36) | TSHRPPARDMEN1GAACYP2C9 | |
| SCHEMBL3095792 | 0.78 | LAP3 (0.35) | TDP1 | |
| SCHEMBL3095789 | 0.78 | LAP3 (0.35) | TDP1 | |
| SCHEMBL3109162 | 0.76 | MEN1 (0.33) | TSHRPPARDMEN1GAACYP2C9 | |
| SCHEMBL3086434 | 0.75 | CPB2 (0.35) | TSHRPPARDMEN1GAACYP2C9 | |
| SCHEMBL3105927 | 0.73 | GABRP (0.36) | TSHRPPARDMEN1GAACYP2C9 | |
| SCHEMBL3098894 | 0.70 | CPB2 (0.33) | TSHRPPARDMEN1GAACYP2C9 | |
| SCHEMBL3108100 | 0.69 | CA12 (0.37) | MEN1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL3087485 | 0.69 | GSR (0.37) | PPARDMEN1KMT2A | |
| SCHEMBL10877831 | 0.68 | TSHR (0.43) | TSHRPPARDGAACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |