Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 2/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956065 | 0.87 | KMT2A (0.43) | TP53MAPTSMN1; SMN2MAOBHTT | |
| SCHEMBL21116465 | 0.77 | TP53 (0.46) | TP53MAPTSMN1; SMN2PPARDMAOB | |
| SCHEMBL16619764 | 0.74 | TP53 (0.43) | TP53MAPTSMN1; SMN2PPARDMAOB | |
| SCHEMBL17107455 | 0.74 | MAOB (0.44) | TP53MAPTSMN1; SMN2PPARDMAOB | |
| SCHEMBL18015849 | 0.72 | MTNR1A (0.45) | TP53MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL21116466 | 0.72 | TP53 (0.46) | TP53MAPTSMN1; SMN2MAOBMTNR1B | |
| SCHEMBL18014739 | 0.72 | TP53 (0.41) | TP53MAPTSMN1; SMN2PPARDMAOB | |
| SCHEMBL30956101 | 0.70 | KDM4E (0.60) | MAPTHTTALDH1A1HPGDMEN1 | |
| SCHEMBL11819605 | 0.70 | NPC1 (0.49) | TP53MAPTSMN1; SMN2MAOBALDH1A1 | |
| SCHEMBL17324189 | 0.68 | MTNR1A (0.40) | TP53MAPTSMN1; SMN2PPARDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005692-A | Preparation of benzofuran derivative by initiating free radical reaction by superelectron donor with heteroatom as center and application | 贵州大学 | 2024-05-10 | — | — | CN | disclosed |