Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CLPP | Q16740 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23531399 | 0.77 | KDM4E (0.68) | KDM4ELMNAMAPTHPGDALDH1A1 | |
| SCHEMBL7775603 | 0.74 | HTT (0.46) | LMNAMAPTHPGDALDH1A1MEN1 | |
| SCHEMBL25936841 | 0.74 | ACP3 (0.62) | MAPTHPGDALDH1A1HTTNPSR1 | |
| SCHEMBL27212825 | 0.72 | KDM4E (0.64) | KDM4ELMNAMAPTHPGDALDH1A1 | |
| SCHEMBL30956100 | 0.70 | TP53 (0.40) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL30956065 | 0.70 | KMT2A (0.43) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL25936994 | 0.69 | HTT (0.55) | LMNAMAPTHPGDALDH1A1MEN1 | |
| SCHEMBL28973814 | 0.69 | ALDH1A1 (0.57) | KDM4ELMNAMAPTHPGDALDH1A1 | |
| SCHEMBL8679316 | 0.69 | CYP3A4 (0.42) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL14802040 | 0.69 | HPGD (0.60) | KDM4ELMNAMAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005692-A | Preparation of benzofuran derivative by initiating free radical reaction by superelectron donor with heteroatom as center and application | 贵州大学 | 2024-05-10 | — | — | CN | disclosed |