SCHEMBL30957421

SCHEMBL30957421

O=C(c1cccc(O)c1)N1CCOCC1

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.71
MGLL Q99685 3/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
KDM4E B2RXH2 1/20 0.62
TSHR P16473 2/20 0.61
RECQL P46063 1/20 0.61
ALDH1A1 P00352 2/20 0.59
PKM P14618 1/20 0.58
ERN1 O75460 1/20 0.58
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
NPC1 O15118 1/20 0.57
TP53 P04637 1/20 0.57
MAPK1 P28482 1/20 0.57
RAB9A P51151 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7069211 1.00 HPGD (0.71) HPGDMGLLL3MBTL1KDM4ETSHR
SCHEMBL10720509 0.90 L3MBTL1 (0.71) HPGDL3MBTL1KDM4ETSHRRECQL
Phenol SCHEMBL28280794 0.85 HPGD (0.76) HPGDL3MBTL1TSHRALDH1A1KMT2A
SCHEMBL28294867 0.85 HPGD (0.71) HPGDL3MBTL1KDM4ETSHRRECQL
SCHEMBL2644377 0.84 HPGD (0.67) HPGDMGLLL3MBTL1ALDH1A1MEN1
SCHEMBL15605882 0.84 SMN1; SMN2 (0.65) HPGDMGLLALDH1A1MEN1KMT2A
SCHEMBL30577960 0.83 L3MBTL1 (0.64) HPGDL3MBTL1KDM4ETSHRRECQL
SCHEMBL1199986 0.83 L3MBTL1 (0.64) HPGDL3MBTL1KDM4ETSHRRECQL
SCHEMBL28860346 0.83 HPGD (1.00) HPGDL3MBTL1KDM4ETSHRRECQL
SCHEMBL30957287 0.83 HPGD (0.68) HPGDMGLLALDH1A1ERN1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598933-A1 PHOSPHORAMIDATE COMPOUNDS AND USES THEREOF Allorion Therapeutics Inc (US) 2025-08-13 EP disclosed
CN-119968377-A Phosphoramidate compounds and uses thereof 安锐生物医药公司 2025-05-09 CN disclosed
WO-2024078392-A1 PHOSPHORAMIDATE COMPOUNDS AND USES THEREOF ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) 2024-04-18 WO disclosed