SCHEMBL3095770

SCHEMBL3095770

NC(CC1C=CC=CC1)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.36
GRIN2D O15399 5/20 0.33
GRIN3B O60391 5/20 0.33
GRIN1 Q05586 5/20 0.33
GRIN2A Q12879 5/20 0.33
GRIN2B Q13224 5/20 0.33
GRIN2C Q14957 5/20 0.33
GRIN3A Q8TCU5 5/20 0.33
PTGS1 P23219 1/20 0.33
SLC7A11 Q9UPY5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3095766 1.00 SIGMAR1 (0.36) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL15372960 1.00 SIGMAR1 (0.36) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL28661477 0.98 SIGMAR1 (0.35) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
Glycine SCHEMBL19327547 0.94 SIGMAR1 (0.33) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL19143724 0.83 GSR (0.37) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30531444 0.83 GRIN2D (0.32) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL19016881 0.79 ALOX15 (0.33) SIGMAR1
SCHEMBL11752477 0.77 SIGMAR1 (0.42) SIGMAR1
SCHEMBL28863951 0.76 FOLH1 (0.36) SIGMAR1
SCHEMBL16866955 0.76 CA2 (0.39) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1919449-A2 ANTIBIOTIC KIT AND COMPOSITION AND USES THEREOF Foamix Ltd. (IL) 2008-05-14 EP claimed
WO-2007099396-A2 ANTIBIOTIC KIT AND COMPOSITION AND USES THEREOF FOAMIX LTD. (US) 2007-09-07 WO claimed
EP-0937156-B1 PREPARATION OF D-AMINO ACIDS BY DIRECT FERMENTATIVE MEANS PCBU SERVICES INC (US) 2003-03-19 EP claimed
US-20240068008-A1 RNase for Improved Microbial Detection and Antimicrobial Susceptibility Testing MICROBEDX, INC. 2024-02-29 US disclosed
CN-117304262-A Peptides with skin whitening activity and uses thereof 凯尔格恩有限公司 2023-12-29 CN disclosed
CN-117304263-A Peptides with skin whitening activity and uses thereof 凯尔格恩有限公司 2023-12-29 CN disclosed
CN-112689641-B Peptides with skin whitening activity and uses thereof 凯尔格恩有限公司 2023-11-07 CN disclosed
CN-112689640-B Peptides with skin whitening activity and uses thereof 凯尔格恩有限公司 2023-10-31 CN disclosed
EP-3551293-B1 RNASE FOR IMPROVED MICROBIAL DETECTION AND ANTIMICROBIAL SUSCEPTIBILITY TESTING MICROBEDX INC (US) 2022-02-09 EP disclosed
CN-112739314-A Compositions and methods for treating cancer and autoimmune diseases 雪松-西奈医学中心 2021-04-30 CN disclosed
CN-112689640-A Peptides having skin whitening activity and uses thereof 凯尔格恩有限公司 2021-04-20 CN disclosed
CN-1239889-A Novel compounds useful as neuroprotective agents LILLY CO ELI (US) 1999-12-29 CN disclosed
WO-1999059573-A1 STABILIZED PHARMACEUTICAL PREPARATIONS OF GAMMA-AMINOBUTYRIC ACID DERIVATIVES AND PROCESS FOR PREPARING THE SAME WARNER-LAMBERT COMPANY (US) 1999-11-25 WO disclosed
US-5962524-A FOR SKINS CASTER (FR) 1999-10-05 US disclosed
WO-1998015274-A1 NOVEL COMPOUNDS USEFUL AS NEURO-PROTECTIVE AGENTS ELI LILLY AND COMPANY (US) 1998-04-16 WO disclosed
US-5204357-A RENIN-INHIBITING AMINO ACID DERIVATIVES HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-20 US disclosed
EP-0028644-A1 IMPENDING OVULATION TEST OSTER, Gerald (US) 1981-05-20 EP disclosed
WO-1980002596-A1 IMPENDING OVULATION TEST OSTER G (US) 1980-11-27 WO disclosed
US-4091201-A FILTRATION, WASHING, ION EXCHANGE CHROMATOGRAPHY THE UPJOHN COMPANY (US) 1978-05-23 US disclosed
US-4029548-A CULTIVATING STREPTOMYCES LEMENSIS THE UPJOHN COMPANY (US) 1977-06-14 US disclosed