Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29266632 | 1.00 | AR (0.40) | ARNPC1RAB9AMEN1KMT2A | |
| SCHEMBL30368362 | 0.85 | MEN1 (0.33) | MEN1KMT2APTGER4SMN1; SMN2L3MBTL1 | |
| SCHEMBL30368062 | 0.82 | ALDH1A1 (0.38) | KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL30970489 | 0.81 | ERN1 (0.44) | ARNPC1RAB9AMEN1KMT2A | |
| SCHEMBL30368321 | 0.80 | KDM2B (0.32) | — | |
| SCHEMBL30301734 | 0.78 | ALB (0.37) | RAB9AMEN1KMT2AMAOAMAOB | |
| SCHEMBL30368399 | 0.78 | THRA (0.34) | MEN1KMT2AMAOAMAOB | |
| SCHEMBL29266679 | 0.78 | THRA (0.34) | MEN1KMT2AMAOAMAOB | |
| Water SCHEMBL2340363 | 0.73 | MRGPRX4 (0.50) | PTGER1PTGER4PTGER3PTGER2MAOB | |
| SCHEMBL3209029 | 0.73 | MAOB (0.42) | PTGER1PTGER4PTGER3PTGER2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317954-A | Indoline as PROTAC compound | 奈奥芬莱有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-118317949-A | Isoindolines as PMS2 inhibitors | 奈奥芬莱有限公司 | 2024-07-09 | — | — | CN | disclosed |