Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.44 |
| ▸ | APLNR | P35414 | 5/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30958099 | 0.92 | APLNR (0.47) | ACEAPLNRC5AR1MC4ROPRK1 | |
| SCHEMBL29569060 | 0.84 | ITGB3 (0.48) | APLNRC5AR1ITGB3ITGAV | |
| SCHEMBL29568833 | 0.83 | ITGB3 (0.48) | APLNRC5AR1ITGB3ITGAV | |
| SCHEMBL29630369 | 0.83 | TRHR (0.41) | ACEOPRM1OPRD1 | |
| SCHEMBL29569355 | 0.83 | C5AR1 (0.55) | APLNRC5AR1MC4RITGB3ITGAV | |
| SCHEMBL29568884 | 0.82 | C5AR1 (0.54) | APLNRC5AR1MC4RITGB3ITGAV | |
| SCHEMBL30958093 | 0.82 | APLNR (0.59) | APLNRC5AR1MC4ROPRK1OPRM1 | |
| SCHEMBL30356636 | 0.81 | APLNR (0.40) | ACEAPLNRC5AR1OPRM1OPRD1 | |
| SCHEMBL29568804 | 0.81 | ACE (0.45) | ACE | |
| SCHEMBL29802052 | 0.81 | ACE (0.48) | ACEC5AR1MC4ROPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649146-B1 | APELIN PEPTIDES AND USES THEREOF | UNIV ALBERTA (CA) | 2024-06-26 | — | — | EP | disclosed |