Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.67 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15544757 | 0.80 | HSD11B1 (1.00) | HSD11B1NOTUMKEAP1MAPTMEN1 | |
| SCHEMBL27901981 | 0.77 | NOTUM (0.72) | HSD11B1NOTUMKEAP1MAPTMEN1 | |
| SCHEMBL4290743 | 0.75 | NOTUM (0.70) | HSD11B1NOTUMKEAP1MAPTMEN1 | |
| SCHEMBL322928 | 0.75 | NOTUM (0.70) | HSD11B1NOTUMKEAP1MAPTMEN1 | |
| SCHEMBL13085444 | 0.74 | KEAP1 (0.91) | NOTUMKEAP1MAPTMEN1KMT2A | |
| SCHEMBL7717627 | 0.74 | NOTUM (0.68) | HSD11B1NOTUMKEAP1MAPTMEN1 | |
| SCHEMBL3210469 | 0.74 | NOTUM (1.00) | NOTUMKEAP1MAPTMEN1KMT2A | |
| SCHEMBL16907562 | 0.74 | NOTUM (0.68) | HSD11B1NOTUMKEAP1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL21496871 | 0.74 | NOTUM (0.68) | HSD11B1NOTUMKEAP1MAPTMEN1 | |
| SCHEMBL546055 | 0.74 | NOTUM (0.68) | HSD11B1NOTUMKEAP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271261-A | Dicarbonyl compound containing cyclobutane segment and synthesis method thereof | 中国科学技术大学 | 2024-07-02 | — | — | CN | disclosed |