Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.82 |
| ▸ | HTR1A | P08908 | 5/20 | 0.82 |
| ▸ | HTR6 | P50406 | 5/20 | 0.82 |
| ▸ | HTR1D | P28221 | 5/20 | 0.82 |
| ▸ | HTR1B | P28222 | 4/20 | 0.82 |
| ▸ | HTR2C | P28335 | 3/20 | 0.82 |
| ▸ | HTR7 | P34969 | 3/20 | 0.82 |
| ▸ | HTR2B | P41595 | 3/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.82 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.82 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.82 |
| ▸ | HTR1E | P28566 | 2/20 | 0.82 |
| ▸ | HTR5A | P47898 | 2/20 | 0.82 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.82 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.82 |
| ▸ | HTR3B | O95264 | 1/20 | 0.82 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.82 |
| ▸ | HTR1F | P30939 | 1/20 | 0.82 |
| ▸ | HTR3A | P46098 | 1/20 | 0.82 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mebufotenin SCHEMBL29993265 | 1.00 | HTR2A (0.82) | HTR2AHTR1AHTR6HTR1DHTR1B | |
| Mebufotenin SCHEMBL29351950 | 0.90 | HTR1D (1.00) | HTR2AHTR1AHTR6HTR1DHTR1B | |
| Mebufotenin SCHEMBL27221706 | 0.90 | HTR1D (1.00) | HTR2AHTR1AHTR6HTR1DHTR1B | |
| Mebufotenin SCHEMBL132733 | 0.90 | HTR1D (1.00) | HTR2AHTR1AHTR6HTR1DHTR1B | |
| Mebufotenin SCHEMBL31098269 | 0.90 | HTR1D (1.00) | HTR2AHTR1AHTR6HTR1DHTR1B | |
| Mebufotenin SCHEMBL25330504 | 0.89 | HTR1D (0.97) | HTR2AHTR1AHTR6HTR1DHTR1B | |
| Mebufotenin SCHEMBL26111484 | 0.89 | HTR1D (0.97) | HTR2AHTR1AHTR6HTR1DHTR1B | |
| Mebufotenin SCHEMBL30601940 | 0.88 | HTR2A (0.64) | HTR2AHTR1AHTR6HTR1DHTR1B | |
| Mebufotenin SCHEMBL30601939 | 0.88 | HTR2A (0.67) | HTR2AHTR1AHTR6HTR1DHTR1B | |
| Mebufotenin SCHEMBL25184829 | 0.88 | HTR2A (0.67) | HTR2AHTR1AHTR6HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4654967-A1 | TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS BY PARENTERAL ADMINISTRATION OF A SINGLE, EFFECTIVE PARENTERAL DOSE OF A SHORT-ACTING PSYCHEDELIC AGENT | Cybin UK Ltd (GB) | 2025-12-03 | — | — | EP | disclosed |
| EP-4601639-A1 | METHOD OF ADMINISTRATION OF A PARENTERAL FORMULATION COMPRISING A PSYCHEDELIC AGENT | Cybin UK Ltd (GB) | 2025-08-20 | — | — | EP | disclosed |
| CN-118450893-A | Injectable and inhalable formulations | 赛本英国有限公司 | 2024-08-06 | — | — | CN | disclosed |
| WO-2024156713-A1 | TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS BY PARENTERAL ADMINISTRATION OF A SINGLE, EFFECTIVE PARENTERAL DOSE OF A SHORT-ACTING PSYCHEDELIC AGENT | CYBIN UK LTD (GB) | 2024-08-02 | — | — | WO | disclosed |