Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962048 | 1.00 | SCN9A (0.39) | SCN9ATP53THRBGPR119HRH3 | |
| SCHEMBL30962071 | 1.00 | SCN9A (0.39) | SCN9ATP53THRBGPR119HRH3 | |
| SCHEMBL30962059 | 1.00 | SCN9A (0.39) | SCN9ATP53THRBGPR119HRH3 | |
| SCHEMBL30962055 | 0.77 | PRKCG (0.40) | SCN9ATP53THRBGPR119HRH3 | |
| SCHEMBL27268982 | 0.77 | PRKCG (0.40) | SCN9ATP53THRBGPR119HRH3 | |
| SCHEMBL8081417 | 0.70 | GPR119 (0.43) | SCN9ATP53THRBGPR119MAPT | |
| SCHEMBL27268851 | 0.70 | CHRM2 (0.42) | THRBGPR119MAPTDPP4 | |
| SCHEMBL24187416 | 0.69 | SCN9A (0.49) | SCN9ATP53THRBGPR119MAPT | |
| SCHEMBL27268908 | 0.69 | GPR119 (0.49) | GPR119MAPTDPP4 | |
| SCHEMBL30962025 | 0.69 | HPGD (0.41) | THRBGPR119MAPTDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638442-A1 | TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS | Uniquest Pty Limited (AU) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024130342-A1 | TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS | UNIQUEST PTY LIMITED (AU) | 2024-06-27 | — | — | WO | disclosed |