Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 11/20 | 0.42 |
| ▸ | JAK1 | P23458 | 9/20 | 0.42 |
| ▸ | TYK2 | P29597 | 5/20 | 0.42 |
| ▸ | JAK2 | O60674 | 8/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.41 |
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | PAK4 | O96013 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.41 |
| ▸ | CLK2 | P49760 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962772 | 0.87 | MAP3K7 (0.44) | JAK3JAK1TYK2JAK2ALK | |
| SCHEMBL30962743 | 0.85 | JAK3 (0.47) | JAK3JAK1TYK2JAK2ALK | |
| SCHEMBL30962817 | 0.82 | LCK (0.43) | JAK3JAK2ALKLCKKDR | |
| SCHEMBL30962677 | 0.80 | NFKB1 (0.37) | LCKKDRMAPK14 | |
| SCHEMBL30962908 | 0.76 | WEE1 (0.43) | JAK3JAK1JAK2LCKKDR | |
| SCHEMBL30962750 | 0.76 | TTK (0.40) | JAK3JAK1JAK2LCKKDR | |
| SCHEMBL30962734 | 0.74 | JAK3 (0.48) | JAK3JAK1TYK2JAK2ALK | |
| SCHEMBL30962773 | 0.73 | PDE4D (0.38) | — | |
| SCHEMBL30962633 | 0.71 | NFKB1 (0.42) | LCK | |
| SCHEMBL30962899 | 0.71 | JAK3 (0.58) | JAK3JAK1TYK2JAK2ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |