Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 5/20 | 0.37 |
| ▸ | ATF1 | P18846 | 3/20 | 0.37 |
| ▸ | LCK | P06239 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.36 |
| ▸ | PDE4A | P27815 | 8/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.36 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | JUN | P05412 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962773 | 0.92 | PDE4D (0.38) | NFKB1ATF1PDE4DPDE4BPDE4A | |
| SCHEMBL30962633 | 0.89 | NFKB1 (0.42) | NFKB1ATF1LCKPDE4DPDE4B | |
| SCHEMBL30962738 | 0.86 | PDE4D (0.39) | NFKB1ATF1PDE4DPDE4BPDE4A | |
| SCHEMBL30962658 | 0.81 | NFKB1 (0.42) | NFKB1ATF1PDE4DPDE4BPDE4A | |
| SCHEMBL30962603 | 0.80 | JAK3 (0.42) | LCKMAPK14KDR | |
| SCHEMBL31737736 | 0.78 | PDE4D (0.44) | NFKB1ATF1PDE4DPDE4BPDE4A | |
| SCHEMBL30962609 | 0.74 | NFKB1 (0.43) | NFKB1ATF1PDE4DPDE4BPDE4A | |
| SCHEMBL31737724 | 0.73 | PDE4D (0.42) | PDE4DPDE4BPDE4APDE4CPDE11A | |
| SCHEMBL30962863 | 0.73 | NFKB1 (0.42) | NFKB1ATF1PDE4DPDE4BPDE4A | |
| SCHEMBL30962730 | 0.73 | POLB (0.46) | NFKB1ATF1PDE4DPDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |