Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 13/20 | 0.39 |
| ▸ | ATF1 | P18846 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.38 |
| ▸ | PDE4A | P27815 | 12/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.38 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962773 | 0.92 | PDE4D (0.38) | PDE4DATF1NFKB1PDE4BPDE4A | |
| SCHEMBL30962609 | 0.89 | NFKB1 (0.43) | PDE4DATF1NFKB1PDE4BPDE4A | |
| SCHEMBL30962677 | 0.86 | NFKB1 (0.37) | PDE4DATF1NFKB1PDE4BPDE4A | |
| SCHEMBL30962772 | 0.82 | MAP3K7 (0.44) | — | |
| SCHEMBL30962658 | 0.80 | NFKB1 (0.42) | PDE4DATF1NFKB1PDE4BPDE4A | |
| SCHEMBL30962730 | 0.79 | POLB (0.46) | PDE4DATF1NFKB1PDE4BPDE4A | |
| SCHEMBL30962894 | 0.77 | CHRNA7 (0.48) | PDE4DATF1NFKB1PDE4BPDE4A | |
| SCHEMBL30962582 | 0.76 | CHRNA7 (0.41) | PDE4DATF1NFKB1PDE4BPDE4A | |
| SCHEMBL30962863 | 0.74 | NFKB1 (0.42) | PDE4DATF1NFKB1PDE4BPDE4A | |
| SCHEMBL30962881 | 0.74 | NFKB1 (0.48) | PDE4DATF1NFKB1PDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |