Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL521746 | 0.92 | SLC6A4 (0.63) | SLC6A4ADAM10ERBB2ALDH1A1TDP1 | |
| SCHEMBL30912591 | 0.92 | SLC6A4 (0.63) | SLC6A4ADAM10ERBB2ALDH1A1TDP1 | |
| SCHEMBL30962789 | 0.84 | ALDH1A1 (0.47) | SLC6A4ADAM10ERBB2ALDH1A1TDP1 | |
| SCHEMBL17631252 | 0.80 | SLC6A4 (0.46) | SLC6A4ADAM10ERBB2ALDH1A1TDP1 | |
| SCHEMBL10036406 | 0.79 | SLC6A4 (0.47) | SLC6A4ADAM10ERBB2ALDH1A1TDP1 | |
| SCHEMBL10036445 | 0.78 | ADAM10 (0.46) | SLC6A4ADAM10ERBB2ALDH1A1TDP1 | |
| SCHEMBL30736527 | 0.78 | SLC6A4 (0.62) | SLC6A4ALDH1A1LMNA | |
| SCHEMBL10036370 | 0.78 | SLC6A4 (0.62) | SLC6A4ALDH1A1LMNA | |
| SCHEMBL30962763 | 0.78 | SLC6A4 (0.62) | SLC6A4ALDH1A1LMNAL3MBTL1RAB9A | |
| SCHEMBL30962651 | 0.78 | ALDH1A1 (0.48) | ADAM10ERBB2ALDH1A1LMNAPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |