Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036172 | 0.88 | SLC6A4 (0.46) | SLC6A4ADAM10ERBB2ACHEALDH1A1 | |
| SCHEMBL521746 | 0.83 | SLC6A4 (0.63) | SLC6A4ADAM10ERBB2ALDH1A1TDP1 | |
| SCHEMBL30912591 | 0.83 | SLC6A4 (0.63) | SLC6A4ADAM10ERBB2ALDH1A1TDP1 | |
| SCHEMBL24179362 | 0.79 | SIRT6 (0.40) | SLC6A4ALDH1A1TDP1LMNAMAPT | |
| SCHEMBL30962736 | 0.79 | SLC6A4 (0.55) | SLC6A4ADAM10ERBB2ACHEALDH1A1 | |
| SCHEMBL24179114 | 0.77 | ROS1 (0.41) | SLC6A4ALDH1A1TDP1LMNA | |
| SCHEMBL17631252 | 0.76 | SLC6A4 (0.46) | SLC6A4ADAM10ERBB2ALDH1A1TDP1 | |
| SCHEMBL3354485 | 0.76 | SLC6A4 (0.47) | SLC6A4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30962789 | 0.76 | ALDH1A1 (0.47) | SLC6A4ADAM10ERBB2ACHEALDH1A1 | |
| SCHEMBL10036445 | 0.75 | ADAM10 (0.46) | SLC6A4ADAM10ERBB2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053606-A1 | ARYLAMINOHETEROCYCLIC CARBOXAMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-26 | — | — | WO | disclosed |