Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | XPO1 | O14980 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962909 | 1.00 | GAA (0.46) | GAANPC1TSHRF2RKMT2A | |
| SCHEMBL30962582 | 0.89 | CHRNA7 (0.41) | NPC1TSHRKMT2ACHRNA7POLB | |
| SCHEMBL30962863 | 0.82 | NFKB1 (0.42) | NPC1TSHRKMT2AALDH1A1XPO1 | |
| SCHEMBL30962583 | 0.82 | NFKB1 (0.47) | KMT2ACHRNA7POLBXPO1 | |
| SCHEMBL30962730 | 0.80 | POLB (0.46) | TSHRKMT2ACHRNA7POLBALDH1A1 | |
| SCHEMBL31361724 | 0.79 | KMT2A (0.54) | GAAKMT2APOLBALDH1A1NPSR1 | |
| SCHEMBL30962627 | 0.79 | PDE4A (0.43) | GAATSHRKMT2ACHRNA7SYK | |
| SCHEMBL30962625 | 0.78 | PDE4D (0.47) | NPC1TSHRMAPK14DHODHALDH1A1 | |
| SCHEMBL30962872 | 0.78 | NFKB1 (0.39) | NPC1TSHRKMT2AMAPK14ALDH1A1 | |
| SCHEMBL30962741 | 0.76 | PDE4A (0.43) | POLBMAPK14DHODHXPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |