Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | ATF1 | P18846 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | XPO1 | O14980 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LCK | P06239 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962863 | 0.92 | NFKB1 (0.42) | NFKB1ATF1HPGDHSD17B10TSHR | |
| SCHEMBL30962582 | 0.89 | CHRNA7 (0.41) | NFKB1ATF1HPGDHSD17B10TSHR | |
| SCHEMBL30962625 | 0.87 | PDE4D (0.47) | NFKB1ATF1HPGDHSD17B10TSHR | |
| SCHEMBL30962887 | 0.85 | NFKB1 (0.45) | NFKB1ATF1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL30962814 | 0.84 | PIN1 (0.45) | NFKB1ATF1RAB9ANPC1XPO1 | |
| SCHEMBL30962730 | 0.82 | POLB (0.46) | NFKB1ATF1HPGDHSD17B10TSHR | |
| SCHEMBL30962627 | 0.79 | PDE4A (0.43) | NFKB1ATF1HPGDHSD17B10TSHR | |
| SCHEMBL30962894 | 0.78 | CHRNA7 (0.48) | NFKB1ATF1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30962916 | 0.78 | GAA (0.46) | TSHRALDH1A1NPC1XPO1KMT2A | |
| SCHEMBL30962909 | 0.78 | GAA (0.46) | TSHRALDH1A1NPC1XPO1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |