Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | ATF1 | P18846 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962863 | 0.94 | NFKB1 (0.42) | ATF1NFKB1KMT2AMEN1MAPT | |
| SCHEMBL30962730 | 0.92 | POLB (0.46) | CHRNA7ATF1NFKB1KMT2AMEN1 | |
| SCHEMBL30962872 | 0.89 | NFKB1 (0.39) | ATF1NFKB1KMT2AMEN1MAPT | |
| SCHEMBL30962625 | 0.89 | PDE4D (0.47) | ATF1NFKB1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL30962916 | 0.89 | GAA (0.46) | CHRNA7KMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL30962909 | 0.89 | GAA (0.46) | CHRNA7KMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL30962894 | 0.87 | CHRNA7 (0.48) | CHRNA7ATF1NFKB1KMT2AMEN1 | |
| SCHEMBL30962814 | 0.86 | PIN1 (0.45) | ATF1NFKB1RAB9APDE4DPDE4A | |
| SCHEMBL30962627 | 0.85 | PDE4A (0.43) | CHRNA7ATF1NFKB1KMT2AMEN1 | |
| SCHEMBL30962583 | 0.84 | NFKB1 (0.47) | CHRNA7ATF1NFKB1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |