Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30963447 | 0.69 | ALDH1A1 (0.39) | KDM5AKDM4CKDM5BKDM4EALDH1A1 | |
| SCHEMBL30963570 | 0.69 | POLB (0.37) | KDM5AKDM4CKDM5B | |
| SCHEMBL16198079 | 0.67 | GPX4 (0.44) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL967912 | 0.62 | ALDH1A1 (0.44) | KDM5BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL23130273 | 0.61 | CYP2C9 (0.49) | KDM5AKDM4CKDM5BALDH1A1HPGD | |
| SCHEMBL15779574 | 0.59 | OXTR (0.48) | KDM5AKDM4CKDM5BKDM4EALDH1A1 | |
| SCHEMBL18725081 | 0.59 | KDM5A (0.37) | KDM5AKDM4CKDM5BALDH1A1HSD17B10 | |
| SCHEMBL15299343 | 0.59 | NPC1 (0.41) | KDM5AKDM4CKDM5BKDM4EALDH1A1 | |
| SCHEMBL19453172 | 0.59 | OXTR (0.48) | ALDH1A1GAAHSD17B10KMT2AOXTR | |
| SCHEMBL9464682 | 0.59 | KDM4E (0.43) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638446-A1 | THIADIAZOLE DERIVATIVES AS INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | Ventus Therapeutics U.S., Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137607-A1 | THIADIAZOLE DERIVATIVES AS INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2024-06-27 | — | — | WO | disclosed |