Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SLC8B1 | Q6J4K2 | 1/20 | 0.38 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.37 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29242310 | 1.00 | PGR (0.41) | PGRBRD4POLBMAPTTP53 | |
| SCHEMBL30965339 | 0.89 | PGR (0.38) | PGRPOLBMAPTTP53PDE4A | |
| SCHEMBL3966480 | 0.89 | PGR (0.38) | PGRPOLBMAPTTP53PDE4A | |
| SCHEMBL30965341 | 0.85 | BRD4 (0.43) | PGRBRD4POLBMAPTTP53 | |
| SCHEMBL29242301 | 0.85 | BRD4 (0.43) | PGRBRD4POLBMAPTTP53 | |
| SCHEMBL29242355 | 0.85 | BRD4 (0.41) | BRD4POLBMAPTTP53CYP1A2 | |
| SCHEMBL30965343 | 0.85 | BRD4 (0.41) | BRD4POLBMAPTTP53CYP1A2 | |
| SCHEMBL29242350 | 0.80 | PGR (0.41) | PGRPOLBMAPTTP53TSHR | |
| SCHEMBL30965344 | 0.80 | PGR (0.41) | PGRPOLBMAPTTP53TSHR | |
| SCHEMBL7463659 | 0.79 | BRD4 (0.51) | PGRBRD4MAPTTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221565-A | 3-Aryl indol-2-one compound with anticancer activity and application thereof in preparation of medicines for treating cancers | 常州大学 | 2024-06-21 | — | — | CN | disclosed |