Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SLC8B1 | Q6J4K2 | 1/20 | 0.38 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29242350 | 1.00 | PGR (0.41) | PGRPBRM1POLBCYP1A2ALDH1A1 | |
| SCHEMBL29242288 | 0.89 | PBRM1 (0.43) | PGRPBRM1POLBCYP1A2ALDH1A1 | |
| SCHEMBL29242289 | 0.83 | TP53 (0.49) | POLBCYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL30965337 | 0.83 | TP53 (0.49) | POLBCYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL30965341 | 0.82 | BRD4 (0.43) | PGRPOLBCYP1A2ALDH1A1NPC1 | |
| SCHEMBL29242301 | 0.82 | BRD4 (0.43) | PGRPOLBCYP1A2ALDH1A1NPC1 | |
| SCHEMBL30965348 | 0.80 | PGR (0.41) | PGRPOLBCYP1A2KMT2AMAPT | |
| SCHEMBL29242310 | 0.80 | PGR (0.41) | PGRPOLBCYP1A2KMT2AMAPT | |
| SCHEMBL5678203 | 0.78 | MAPT (0.44) | PGRPBRM1CYP1A2ALDH1A1KDM4E | |
| SCHEMBL30965343 | 0.77 | BRD4 (0.41) | PBRM1POLBCYP1A2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221565-A | 3-Aryl indol-2-one compound with anticancer activity and application thereof in preparation of medicines for treating cancers | 常州大学 | 2024-06-21 | — | — | CN | disclosed |