SCHEMBL30965353

SCHEMBL30965353

Cc1cn([C@H]2C[C@H](O)[C@@H](COO[Si](C)(C)C(C)(C)C)O2)c(=O)[nH]c1=O

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.59
TK1 P04183 3/20 0.56
TOP2A P11388 2/20 0.55
BCHE P06276 1/20 0.55
TYMS P04818 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888123 0.90 TOP2A (0.66) POLBTK1TOP2A
SCHEMBL22315382 0.90 TOP2A (0.66) POLBTK1TOP2A
SCHEMBL21489337 0.90 TOP2A (0.66) POLBTK1TOP2A
SCHEMBL12570184 0.90 TOP2A (0.66) POLBTK1TOP2A
SCHEMBL888122 0.90 TOP2A (0.66) POLBTK1TOP2A
SCHEMBL31289405 0.90 TOP2A (0.66) POLBTK1TOP2A
SCHEMBL7571044 0.85 TK1 (0.66) POLBTK1BCHETYMS
SCHEMBL19101672 0.85 POLB (0.66) POLBTK1BCHETYMS
SCHEMBL6046227 0.85 POLB (0.66) POLBTK1BCHETYMS
SCHEMBL13939942 0.84 POLB (0.64) POLBTK1TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118339173-A Method for preparing polynucleotide ATD生物有限公司 2024-07-12 CN disclosed