Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | TYMS | P04818 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046227 | 0.91 | POLB (0.66) | TK1POLBTYMSBCHE | |
| SCHEMBL19101672 | 0.91 | POLB (0.66) | TK1POLBTYMSBCHE | |
| SCHEMBL12918450 | 0.91 | TK1 (0.69) | TK1POLBTYMSBCHE | |
| SCHEMBL17236294 | 0.91 | TK1 (0.69) | TK1POLBTYMSBCHE | |
| SCHEMBL522285 | 0.91 | TK1 (0.69) | TK1POLBTYMSBCHE | |
| SCHEMBL4198253 | 0.91 | TK1 (0.69) | TK1POLBTYMSBCHE | |
| SCHEMBL17232081 | 0.91 | TK1 (0.69) | TK1POLBTYMSBCHE | |
| SCHEMBL135209 | 0.91 | TK1 (0.69) | TK1POLBTYMSBCHE | |
| SCHEMBL22943603 | 0.91 | TK1 (0.69) | TK1POLBTYMSBCHE | |
| SCHEMBL8163243 | 0.89 | POLB (0.64) | TK1POLBTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105792832-B | Organic compounds for the treatment of hepatitis B virus | 诺华股份有限公司 | 2021-03-23 | — | — | CN | claimed |
| EP-3083654-A1 | 4'-OR NUCLEOSIDES FOR THE TREATMENT OF HCV | Idenix Pharmaceuticals LLC (US) | 2016-10-26 | — | — | EP | claimed |
| WO-2015095419-A1 | 4'-OR NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS, INC. (US) | 2015-06-25 | — | — | WO | claimed |
| EP-0741741-B1 | MODIFIED OLIGONUCLEOTIDES | NOVARTIS AG (CH) | 2002-08-28 | — | — | EP | disclosed |
| US-6066447-A | INCLUDING NUCLEOSIDE DIMERS WITH MODIFIED BACKBONES; FOR VIRICIDES AND ANTISENSE AGENTS | NOVARTIS CORPORATION (US) | 2000-05-23 | — | — | US | disclosed |
| EP-0741741-A1 | MODIFIED OLIGONUCLEOTIDES | Novartis AG (CH) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020597-A1 | MODIFIED OLIGONUCLEOTIDES | CIBA-GEIGY AG (CH) | 1995-08-03 | — | — | WO | disclosed |