Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24065504 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1CYP19A1TSHRHRH1 | |
| SCHEMBL30965507 | 0.81 | BRD4 (0.42) | ALDH1A1CYP19A1HRH1LMNAMEN1 | |
| SCHEMBL24065389 | 0.81 | BRD4 (0.42) | ALDH1A1CYP19A1HRH1LMNAMEN1 | |
| SCHEMBL30965485 | 0.80 | CYP19A1 (0.54) | KDM4EALDH1A1CYP19A1TSHRLMNA | |
| SCHEMBL24065467 | 0.80 | CYP19A1 (0.54) | KDM4EALDH1A1CYP19A1TSHRLMNA | |
| SCHEMBL24065505 | 0.77 | RAF1 (0.42) | KDM4EALDH1A1CYP19A1TSHRMAPT | |
| SCHEMBL30965462 | 0.77 | RAF1 (0.42) | KDM4EALDH1A1CYP19A1TSHRMAPT | |
| SCHEMBL24065466 | 0.77 | CYP19A1 (0.71) | ALDH1A1CYP19A1MAPT | |
| SCHEMBL30965506 | 0.77 | CYP19A1 (0.71) | ALDH1A1CYP19A1MAPT | |
| SCHEMBL31726183 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1CYP19A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513032-B | 4-Substituted phenyl-1, 3, 5-triazine derivatives as modulators of TRK receptors | 阿泽克制药公司 | 2024-07-02 | — | — | CN | disclosed |