Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965508 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1CYP19A1TSHRHRH1 | |
| SCHEMBL30965507 | 0.81 | BRD4 (0.42) | ALDH1A1CYP19A1HRH1LMNAMEN1 | |
| SCHEMBL24065389 | 0.81 | BRD4 (0.42) | ALDH1A1CYP19A1HRH1LMNAMEN1 | |
| SCHEMBL30965485 | 0.80 | CYP19A1 (0.54) | KDM4EALDH1A1CYP19A1TSHRLMNA | |
| SCHEMBL24065467 | 0.80 | CYP19A1 (0.54) | KDM4EALDH1A1CYP19A1TSHRLMNA | |
| SCHEMBL24065505 | 0.77 | RAF1 (0.42) | KDM4EALDH1A1CYP19A1TSHRMAPT | |
| SCHEMBL30965462 | 0.77 | RAF1 (0.42) | KDM4EALDH1A1CYP19A1TSHRMAPT | |
| SCHEMBL24065466 | 0.77 | CYP19A1 (0.71) | ALDH1A1CYP19A1MAPT | |
| SCHEMBL30965506 | 0.77 | CYP19A1 (0.71) | ALDH1A1CYP19A1MAPT | |
| SCHEMBL31726183 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1CYP19A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840524-B2 | 4-substituted phenyl-1,3,5-triazine derivatives as modulators of TrK receptors | AlzeCure Pharma AB (SE) | 2023-12-12 | — | — | US | disclosed |
| US-11840524-B2 | 4-substituted phenyl-1,3,5-triazine derivatives as modulators of TrK receptors | AlzeCure Pharma AB (SE) | 2023-12-12 | — | — | US | disclosed |
| US-20210371402-A1 | 4-SUBSTITUTED PHENYL-1,3,5-TRIAZINE DERIVATIVES AS MODULATORS OF TRK RECEPTORS | AlzeCure Pharma AB (SE) | 2021-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11840524-B2 | 4-substituted phenyl-1,3,5-triazine derivatives as modulators of TrK receptors | NTRK2, NTRK3, BDNF | KDM4E 2426/4885ALDH1A1 2719/4885CYP19A1 1282/4885 |
| US-20210371402-A1 | 4-SUBSTITUTED PHENYL-1,3,5-TRIAZINE DERIVATIVES AS MODULATORS OF TRK RECEPTORS | NTRK2, NTRK3, BDNF | KDM4E 2426/4885ALDH1A1 2719/4885CYP19A1 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.