Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24065467 | 1.00 | CYP19A1 (0.54) | CYP19A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL30965469 | 0.83 | CYP19A1 (0.55) | CYP19A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL24065461 | 0.83 | CYP19A1 (0.55) | CYP19A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL24065504 | 0.80 | KDM4E (0.47) | CYP19A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL30965508 | 0.80 | KDM4E (0.47) | CYP19A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL24065510 | 0.80 | CYP19A1 (0.83) | CYP19A1KMT2AALDH1A1 | |
| SCHEMBL30965499 | 0.80 | CYP19A1 (0.83) | CYP19A1KMT2AALDH1A1 | |
| SCHEMBL8936751 | 0.79 | CYP19A1 (0.40) | CYP19A1KDM4ENPSR1PKMTDP1 | |
| SCHEMBL14864858 | 0.76 | MAPT (0.58) | CYP19A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL23292617 | 0.75 | MAPT (0.53) | CYP19A1KDM4ETSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513032-B | 4-Substituted phenyl-1, 3, 5-triazine derivatives as modulators of TRK receptors | 阿泽克制药公司 | 2024-07-02 | — | — | CN | disclosed |