Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 6/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1560025 | 0.83 | ACHE (0.35) | — | |
| SCHEMBL1559890 | 0.82 | GAA (0.40) | PLK1 | |
| SCHEMBL1560822 | 0.81 | OPRM1 (0.35) | — | |
| SCHEMBL2302378 | 0.81 | PLA2G7 (0.37) | SMN1; SMN2 | |
| SCHEMBL30135744 | 0.80 | PLK2 (0.35) | SMN1; SMN2PLK1BRD4BRDT | |
| SCHEMBL1559398 | 0.80 | PLK2 (0.35) | SMN1; SMN2PLK1BRD4BRDT | |
| SCHEMBL2296654 | 0.80 | ADORA2A (0.34) | SMN1; SMN2PLK1 | |
| SCHEMBL1560746 | 0.77 | PLK1 (0.51) | SMN1; SMN2PLK1BRD4BRDT | |
| SCHEMBL1560752 | 0.77 | PLK1 (0.34) | SMN1; SMN2PLK1BRD4BRDT | |
| SCHEMBL1559681 | 0.77 | PLK1 (0.53) | SMN1; SMN2PLK1BRD4BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| CN-119790057-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2025-04-08 | — | — | CN | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |