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Sugi Predict / Compounds / SCHEMBL30965799

SCHEMBL30965799

SCHEMBL30965799

CC(C)(C)OC(=O)NC1CCN(CCC2CCN(c3cc(F)c(NC4CCC(=O)NC4=O)cc3F)CC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DRD2 P14416 7/20 0.44
▸ DRD3 P35462 2/20 0.44
▸ DDB1 Q16531 9/20 0.41
▸ CRBN Q96SW2 9/20 0.41
▸ KCNA3 P22001 1/20 0.39
▸ PARP1 P09874 1/20 0.36
▸ PARP2 Q9UGN5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30965703 0.93 CRBN (0.42) DRD2DRD3DDB1CRBNKCNA3
SCHEMBL30965660 0.92 DRD2 (0.40) DRD2DRD3DDB1CRBN
SCHEMBL31712320 0.92 CRBN (0.46) DRD2DRD3DDB1CRBNKCNA3
SCHEMBL30965552 0.88 CRBN (0.43) DRD2DRD3DDB1CRBN
SCHEMBL30965618 0.87 CRBN (0.45) DRD2DRD3DDB1CRBNKCNA3
SCHEMBL30965558 0.87 DRD2 (0.45) DRD2DRD3DDB1CRBNKCNA3
SCHEMBL30965610 0.86 DDB1 (0.53) DDB1CRBN
SCHEMBL30981399 0.85 DRD2 (0.53) DRD2DRD3DDB1CRBN
SCHEMBL31334275 0.85 CRBN (0.46) DRD2DRD3DDB1CRBNPARP1
SCHEMBL30915142 0.85 CRBN (0.49) DRD2DRD3DDB1CRBNKCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658658-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND Uppthera, Inc. (KR) 2025-12-10 — — EP disclosed
WO-2024162828-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND UPPTHERA, INC. (KR) 2024-08-08 — — WO disclosed