Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28686105 | 1.00 | CHRNA7 (0.55) | CHRNA7BCHEACHEEPHX2CYP2D6 | |
| SCHEMBL6556626 | 0.86 | CHRNA7 (0.59) | CHRNA7MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5166546 | 0.84 | CHRNA7 (0.58) | CHRNA7MEN1KMT2A | |
| SCHEMBL1459283 | 0.83 | MEN1 (0.52) | EPHX2POLBMAPTMEN1KMT2A | |
| SCHEMBL14540064 | 0.83 | SMN1; SMN2 (0.52) | POLBMAPT | |
| SCHEMBL14540182 | 0.82 | FPR1 (0.45) | CHRNA7BCHEACHECHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL4285765 | 0.82 | MEN1 (0.51) | EPHX2POLBMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5168545 | 0.82 | SMN1; SMN2 (0.54) | POLBMAPT | |
| SCHEMBL1460457 | 0.81 | PTPN1 (0.48) | CHRM3 | |
| SCHEMBL14539956 | 0.81 | DRD2 (0.45) | CHRNA7BCHEACHECHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113950477-B | Granulin precursor modulators and methods of use thereof | 阿库达医疗公司 | 2024-07-05 | — | — | CN | disclosed |