Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GALK1 | P51570 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15509351 | 0.80 | METAP2 (0.55) | ALDH1A1BACE1SMN1; SMN2LMNAMAPT | |
| SCHEMBL15509310 | 0.80 | AKR1C3 (0.53) | ALDH1A1BACE1HTTMAPTMAOB | |
| SCHEMBL15509479 | 0.80 | METAP2 (0.55) | BACE1HTTMEN1NPC1LMNA | |
| SCHEMBL15509632 | 0.80 | METAP2 (0.55) | ALDH1A1BACE1HTTMEN1LMNA | |
| SCHEMBL199940 | 0.78 | ALDH1A1 (0.48) | ALDH1A1BACE1KMT2AHSD17B10HPGD | |
| SCHEMBL8928083 | 0.76 | ALDH1A1 (0.50) | PTPN1ALDH1A1BACE1HTTSMN1; SMN2 | |
| SCHEMBL16050857 | 0.75 | PSMB5 (0.44) | ALDH1A1BACE1HTTSMN1; SMN2MEN1 | |
| SCHEMBL22064851 | 0.74 | CYP2A6 (0.50) | PTPN1ALDH1A1BACE1HTTSMN1; SMN2 | |
| SCHEMBL22064850 | 0.74 | ALDH1A1 (0.47) | PTPN1ALDH1A1BACE1HTTSMN1; SMN2 | |
| SCHEMBL20663065 | 0.74 | PTGS1 (0.58) | PTPN1ALDH1A1BACE1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3662996-A2 | MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS | Verbio Vereinigte BioEnergie AG (DE) | 2020-06-10 | — | — | EP | claimed |
| EP-2703081-B1 | MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS | XIMO AG (CH) | 2019-08-07 | — | — | EP | claimed |
| US-9919299-B2 | Metathesis catalysts and reactions using the catalysts | XIMO AG (CH) | 2018-03-20 | — | — | US | claimed |
| US-9499455-B2 | Process for the selective dimerisation of ethylene to 1-butene | IFP Energies Nouvelles (FR) | 2016-11-22 | — | — | US | claimed |
| US-20160030936-A1 | METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS | VERBIO SE (DE) | 2016-02-04 | — | — | US | claimed |
| EP-2969204-A2 | MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS | XiMo AG (CH) | 2016-01-20 | — | — | EP | claimed |
| US-20140309466-A1 | METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS | VERBIO SE (DE) | 2014-10-16 | — | — | US | claimed |
| WO-2014139679-A2 | METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS | XIMO AG (CH) | 2014-09-18 | — | — | WO | claimed |
| EP-2703081-A1 | Molybdenum and tungsten complexes as olefin metathesis catalysts and reactions using the catalysts | XiMo AG (CH) | 2014-03-05 | — | — | EP | claimed |
| US-7148296-B2 | Capped poly(arylene ether) composition and process | GENERAL ELECTRIC COMPANY (US) | 2006-12-12 | — | — | US | claimed |
| US-7101923-B2 | Flame-retardant thermoset composition, method, and article | GENERAL ELECTRIC COMPANY (US) | 2006-09-05 | — | — | US | claimed |
| US-20060167142-A9 | FLAME-RETARDANT THERMOSET COMPOSITION, METHOD, AND ARTICLE | GENERAL ELECTRIC COMPANY | 2006-07-27 | — | — | US | claimed |
| US-7067595-B2 | Poly (arylene ether) composition and method | GENERAL ELECTRIC COMPANY (US) | 2006-06-27 | — | — | US | claimed |
| WO-2006023371-A1 | FUNCTIONALIZED POLY(ARYLENE ETHER) COMPOSITION AND METHOD | GENERAL ELECTRIC COMPANY (US) | 2006-03-02 | — | — | WO | claimed |
| US-20060041086-A1 | Functionalized poly(arylene ether) composition and method | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2006-02-23 | — | — | US | claimed |
| US-6903042-B2 | Catalytic composition and process for oligomerizing ethylene, in particular to 1-hexene | INSTITUT FRANCAIS DU PETROLE (FR) | 2005-06-07 | — | — | US | claimed |
| US-20050075426-A1 | Flame-retardant thermoset composition, method, and article | CITIBANK, N.A., AS COLLATERAL AGENT | 2005-04-07 | — | — | US | claimed |
| US-20050075463-A1 | Poly (arylene ether) composition and method | CITIBANK, N.A., AS COLLATERAL AGENT | 2005-04-07 | — | — | US | claimed |
| US-20050075427-A1 | Flame-retardant thermoset composition, method, and article | GENERAL ELECTRIC COMPANY | 2005-04-07 | — | — | US | claimed |
| US-20050075462-A1 | Capped poly(arylene ether) composition and process | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2005-04-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309466-A1 | METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS | MSMO1, PYM1, SQLE | PTPN1 4326/4885ALDH1A1 2361/4885BACE1 1981/4885 |
| US-20160030936-A1 | METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS | MSMO1, SQLE, PYM1 | PTPN1 4333/4885ALDH1A1 1956/4885BACE1 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.