SCHEMBL199940

SCHEMBL199940

[O]c1c(-c2ccccc2)cccc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
HSD17B10 Q99714 2/20 0.48
HPGD P15428 1/20 0.48
BCL2L1 Q07817 1/20 0.48
CYP2A6 P11509 1/20 0.48
MAPK1 P28482 1/20 0.48
HNF4A P41235 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
TDP1 Q9NUW8 1/20 0.44
BCAT2 O15382 1/20 0.44
BACE1 P56817 1/20 0.43
PLK4 O00444 1/20 0.43
MAPK9 P45984 1/20 0.43
LIMK1 P53667 1/20 0.43
CLK4 Q9HAZ1 1/20 0.43
AKT3 Q9Y243 1/20 0.43
METAP2 P50579 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3568992 0.83 KDM4E (0.44) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL14657961 0.83 HTT (0.43) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL9323547 0.83 HPGD (0.62) ALDH1A1HSD17B10HPGDBCL2L1MAPK1
SCHEMBL3563149 0.79 PDCD1 (0.50) ALDH1A1HSD17B10HPGDBCL2L1HNF4A
SCHEMBL309669 0.78 PTPN1 (0.50) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL4845202 0.78 ESR2 (0.48) ALDH1A1HPGD
SCHEMBL2261916 0.78 CA2 (0.40) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Benzene SCHEMBL28035419 0.77 ALDH1A1 (0.61) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL21447 0.77 ALDH1A1 (0.61) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL2361430 0.77 ALDH1A1 (0.61) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11779911-B2 Production of fatty olefin derivatives via olefin metathesis PROVIVI, INC. (US) 2023-10-10 US claimed
CN-115215748-A Production of aliphatic olefin derivatives by olefin metathesis 普罗维维公司 2022-10-21 CN claimed
US-20220032280-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS PROVIVI, INC. (US) 2022-02-03 US claimed
EP-3749674-A1 MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-12-16 EP claimed
US-20200369697-A1 MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2020-11-26 US claimed
EP-3662996-A2 MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS Verbio Vereinigte BioEnergie AG (DE) 2020-06-10 EP claimed
CN-110603240-A Synthesis of pheromones and related substances via olefin metathesis 普罗维维公司 2019-12-20 CN claimed
WO-2019157376-A1 MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2019-08-15 WO claimed
US-10343153-B2 Metathesis catalysts and reactions using the catalysts XIMO AG (CH) 2019-07-09 US claimed
EP-3377465-A2 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS Provivi, Inc. (US) 2018-09-26 EP claimed
CN-105555402-A Metathesis catalyst and reaction using the same XIMO AG 2016-05-04 CN claimed
US-20160030936-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS VERBIO SE (DE) 2016-02-04 US claimed
EP-2969204-A2 MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS XiMo AG (CH) 2016-01-20 EP claimed
US-20150273456-A1 NOVEL CATALYTIC COMPOSITION AND PROCESS FOR OLIGOMERIZING ETHYLENE INTO 1-HEXENE IFP Energies Nouvelles (FR) 2015-10-01 US claimed
CN-104941682-A Novel catalytic composition and process for oligomerizing ethylene into 1-hexene IFP Energies Nouvelles 2015-09-30 CN claimed
US-20140309466-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS VERBIO SE (DE) 2014-10-16 US claimed
WO-2014139679-A2 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS XIMO AG (CH) 2014-09-18 WO claimed
EP-2703081-A1 Molybdenum and tungsten complexes as olefin metathesis catalysts and reactions using the catalysts XiMo AG (CH) 2014-03-05 EP claimed
US-6903042-B2 Catalytic composition and process for oligomerizing ethylene, in particular to 1-hexene INSTITUT FRANCAIS DU PETROLE (FR) 2005-06-07 US claimed
CN-1424148-A Catalytic composition and improved method for ethylene-oligosynthetic 1-ethene INST FRANCAIS DU PETROLE (FR) 2003-06-18 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10343153-B2 Metathesis catalysts and reactions using the catalysts MSMO1, SQLE, MOGAT2 ALDH1A1 994/4885HSD17B10 479/4885HPGD 690/4885
US-20200369697-A1 MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS MSRB3, MMAB, CYB5R3 ALDH1A1 1160/4885HSD17B10 964/4885HPGD 1439/4885
US-20140309466-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS MSMO1, PYM1, SQLE ALDH1A1 2361/4885HSD17B10 1045/4885HPGD 3280/4885
US-20160030936-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS MSMO1, SQLE, PYM1 ALDH1A1 1956/4885HSD17B10 853/4885HPGD 3110/4885
US-11779911-B2 Production of fatty olefin derivatives via olefin metathesis SREBF1, F2, SREBF2 ALDH1A1 1913/4885HSD17B10 99/4885HPGD 1545/4885
US-20220032280-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS SREBF1, F2, SREBF2 ALDH1A1 1913/4885HSD17B10 99/4885HPGD 1545/4885
US-20150273456-A1 NOVEL CATALYTIC COMPOSITION AND PROCESS FOR OLIGOMERIZING ETHYLENE INTO 1-HEXENE XRN2, XDH, SOD1 ALDH1A1 4200/4885HSD17B10 2748/4885HPGD 1080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.