Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 6/20 | 0.70 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | ALDH3A1 | P30838 | 5/20 | 0.64 |
| ▸ | CASP3 | P42574 | 2/20 | 0.63 |
| ▸ | CES1 | P23141 | 4/20 | 0.61 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026196 | 0.89 | CHRM5 (0.72) | CHRM5CHRM3ALDH1A1ALDH3A1CASP3 | |
| SCHEMBL12930258 | 0.83 | CHRM5 (0.81) | CHRM5CHRM3ALDH1A1ALDH3A1CASP3 | |
| SCHEMBL30030790 | 0.83 | CHRM5 (1.00) | CHRM5CHRM3ALDH1A1ALDH3A1CES1 | |
| SCHEMBL27881830 | 0.83 | ALDH1A1 (0.64) | CHRM5CHRM3ALDH1A1ALDH3A1CASP3 | |
| SCHEMBL3020942 | 0.83 | CASP3 (0.61) | CHRM5CHRM3ALDH1A1ALDH3A1CASP3 | |
| SCHEMBL12930211 | 0.83 | CHRM5 (0.76) | CHRM5CHRM3ALDH1A1ALDH3A1CASP3 | |
| SCHEMBL28704458 | 0.82 | CHRM5 (0.63) | CHRM5CHRM3ALDH1A1ALDH3A1CASP3 | |
| SCHEMBL29417352 | 0.82 | CHRM5 (0.63) | CHRM5CHRM3ALDH1A1ALDH3A1CASP3 | |
| SCHEMBL28336739 | 0.81 | CHRM5 (0.49) | CHRM5CHRM3ALDH1A1ALDH3A1CASP3 | |
| SCHEMBL18954872 | 0.81 | CHRM5 (0.55) | CHRM5CHRM3ALDH1A1ALDH3A1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459390-B | 3-Hydroxy oxindole derivative containing Z-type 1, 4-dicarbonyl olefin, and preparation method and application thereof | SUN YAT-SEN UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-118459390-A | 3-Hydroxy oxindole derivative containing Z-type 1, 4-dicarbonyl olefin, and preparation method and application thereof | 中山大学 | 2024-08-09 | — | — | CN | disclosed |