Mandelic Acid

Mandelic Acid

SCHEMBL30967671

CCC(=O)Oc1cc(OC)c(OC)c(OC)c1.O=C(O)C(O)c1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.45
MAPK1 P28482 2/20 0.45
KMT2A Q03164 4/20 0.44
MEN1 O00255 2/20 0.44
BLM P54132 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TSHR P16473 1/20 0.44
HTR1A P08908 1/20 0.42
ELANE P08246 1/20 0.42
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TP53 P04637 1/20 0.40
CACNA2D1 P54289 1/20 0.40
CACNA1B Q00975 1/20 0.40
CACNB1 Q02641 1/20 0.40
CACNA1C Q13936 1/20 0.40
ATM Q13315 1/20 0.40
ESR1 P03372 1/20 0.40
HIF1A Q16665 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mandelic Acid SCHEMBL30967680 0.87 LMNA (0.50) LMNAMAPK1KMT2AMEN1BLM
Mandelic Acid SCHEMBL30967655 0.85 TSHR (0.58) LMNAMAPK1BLMNPSR1TSHR
Mandelic Acid SCHEMBL30967611 0.85 TSHR (0.58) LMNAMAPK1BLMNPSR1TSHR
Mandelic Acid SCHEMBL30967690 0.85 KMT2A (0.47) LMNAMAPK1KMT2AMEN1BLM
SCHEMBL7131011 0.82 KMT2A (0.50) MAPK1KMT2AMEN1MAPTSMN1; SMN2
Mandelic Acid SCHEMBL30967597 0.82 MTNR1A (0.48) LMNAMAPK1HTR1AELANE
SCHEMBL30967665 0.80 BLM (0.46) LMNAMAPK1KMT2ABLMNPSR1
SCHEMBL30967630 0.79 ESR1 (0.50) KMT2ABLMNPSR1TSHRELANE
SCHEMBL30967609 0.77 ESR1 (0.58) LMNAKMT2ABLMNPSR1TSHR
SCHEMBL30967683 0.77 BLM (0.46) MAPK1KMT2AMEN1BLMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105203-A1 NOVEL ANTI-SENESCENCE COMPOUNDS VITEXIA APS (DK) 2024-05-23 WO disclosed