Mandelic Acid

Mandelic Acid

SCHEMBL30967690

CCC(=O)Oc1cc(OC)ccc1OC.O=C(O)C(O)c1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 3/20 0.45
MAPK1 P28482 1/20 0.45
NPSR1 Q6W5P4 2/20 0.44
BLM P54132 1/20 0.44
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.42
ELANE P08246 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30967665 0.87 BLM (0.46) KMT2ATDP1L3MBTL1LMNAMAPK1
Mandelic Acid SCHEMBL30967611 0.85 TSHR (0.58) TDP1L3MBTL1LMNAMAPK1NPSR1
Mandelic Acid SCHEMBL30967655 0.85 TSHR (0.58) TDP1L3MBTL1LMNAMAPK1NPSR1
SCHEMBL27728358 0.85 CA12 (0.57) KMT2ALMNANPSR1HSD17B10CA12
Mandelic Acid SCHEMBL30967671 0.85 LMNA (0.45) KMT2AMEN1LMNAMAPK1NPSR1
Mandelic Acid SCHEMBL30967597 0.85 MTNR1A (0.48) L3MBTL1LMNAMAPK1ELANE
Mandelic Acid SCHEMBL30967680 0.84 LMNA (0.50) KMT2AMEN1LMNAMAPK1NPSR1
SCHEMBL30967642 0.81 ACHE (0.47) L3MBTL1LMNANPSR1BLMTSHR
SCHEMBL15559042 0.81 ALOX15 (0.57) KMT2AL3MBTL1LMNANPSR1HSD17B10
SCHEMBL30967609 0.80 ESR1 (0.58) KMT2AL3MBTL1LMNANPSR1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105203-A1 NOVEL ANTI-SENESCENCE COMPOUNDS VITEXIA APS (DK) 2024-05-23 WO disclosed