Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29336965 | 1.00 | KDM4E (0.38) | KDM4EKMT2AATMMEN1TSHR | |
| SCHEMBL31284578 | 0.89 | KDM4E (0.43) | KDM4EKMT2AATMMEN1TSHR | |
| SCHEMBL27984139 | 0.89 | KDM4E (0.43) | KDM4EKMT2AATMMEN1TSHR | |
| SCHEMBL34471907 | 0.78 | KMT2A (0.41) | KDM4EKMT2AATMMEN1TSHR | |
| SCHEMBL27094100 | 0.77 | L3MBTL1 (0.40) | KDM4EKMT2AATMMEN1MAPK1 | |
| SCHEMBL29993025 | 0.77 | L3MBTL1 (0.40) | KDM4EKMT2AATMMEN1MAPK1 | |
| SCHEMBL31053240 | 0.77 | PKM (0.44) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL671835 | 0.77 | PKM (0.44) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL16396597 | 0.75 | ALDH1A1 (0.46) | KDM4EKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL5741892 | 0.75 | AKR1B1 (0.48) | KDM4ECYP2C9CYP2C19LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |