Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968132 | 1.00 | PTAFR (0.35) | PTAFROPRM1OPRD1HRH3ADRA2A | |
| SCHEMBL30968042 | 1.00 | PTAFR (0.35) | PTAFROPRM1OPRD1HRH3ADRA2A | |
| SCHEMBL30967987 | 0.88 | PTAFR (0.36) | PTAFROPRM1OPRD1HRH3ADRA2A | |
| SCHEMBL30968105 | 0.88 | POLB (0.32) | OPRM1OPRD1GPR142 | |
| SCHEMBL31065783 | 0.85 | PLD3 (0.32) | GPR142 | |
| SCHEMBL31065780 | 0.85 | PLD3 (0.32) | GPR142 | |
| SCHEMBL31065775 | 0.85 | PLD3 (0.32) | GPR142 | |
| SCHEMBL30968089 | 0.84 | PARP1 (0.33) | PTAFRHRH3ADRA2AMCHR1GPR142 | |
| SCHEMBL30968015 | 0.84 | PARP1 (0.33) | PTAFRHRH3ADRA2AMCHR1GPR142 | |
| SCHEMBL30968069 | 0.81 | MAPK1 (0.38) | ADRA2AMCHR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131942-A1 | CYCLOPROPANE TLR7 AND TLR8 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2024-06-27 | — | — | WO | disclosed |
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |